Lysine: biological role and use in medicine. The benefits and significance of lysine for the human body Lysine: consumer reviews

Amino acids, which are necessary for a person for vital processes in the body, are divided into nonessential - they can be synthesized on their own, and irreplaceable - they must come from food.

It is to the essential amino acids that lysine belongs, which will be discussed today.

Characteristics and influence

Lysine refers to an amino acid that is essential for the normal existence of a person, it is found in almost all proteins present in the body.

The substance is presented in the form of a chemical formula: C6H14N2O2.

Did you know? Lysine was first isolated from casein in 1889 by E. Drexel, and already in 1955, scientists from the United States managed to create lysine hydrochloride.

Lysine is the first of the limiting amino acids that are required for proper digestion of dietary proteins. If this amino acid is not enough, then regardless of the amount of protein that enters the body, it will not be digested normally and will be accompanied by a shortage.

It is classified as an essential compound for the growth of muscle tissue, as a synthesizing element of collagen - a component of connective tissue and as an important component for maintaining the immune system.
In the process of aging, the human body must receive more and more of this amino acid, especially for men.

Since the main part of this component enters a person with food, in the case of an incorrect and unbalanced diet, an acute deficiency occurs, which affects all processes in the body.

The same condition can be observed in the case of a vegetarian diet for humans, when the bulk of the food does not contain protein, especially of animal origin.

There are many directions in the influence of lysine on the body, which are presented in the form:

Fight cholesterol. Once in the liver, the amino acid becomes carnitine, which is known to fight excess fats and "bad" cholesterol.

Strengthening bone tissue. Due to the fact that calcium itself is quickly excreted from the body, the component in question allows you to slow down this process and helps to strengthen bone tissue.
Antiviral effects on the body associated with herpes diseases. Lysine is often used as an integral component in the treatment of viral diseases, due to its good antiviral effect. Also, some doctors are inclined to think that using a special diet high in amino acids can prevent herpes outbreaks.

Effects on growth rate in children. Since the amino acid belongs to the protein components, it increases the growth rate in children and directly affects the cause of growth arrest if the child's body feels a lack of the main amino acid.
Protection against stress and anxiety. The amino acid allows you to regulate the emotional state of a person, improves mood, removes anxiety, and prevents nervous disorders.
Pain reliever. This amino acid is known to have anti-inflammatory and analgesic effects. At the moment, additional studies are being carried out on this matter, since this effect was discovered relatively recently.
Effects on the heart muscle. It has been proven that the component is able to alleviate angina pectoris if the body has enough vitamin C.

Important! There are two types of lysine: D and L, but the human body can only assimilate the L-type.

Therefore, in order for the body to receive the necessary daily allowance, it is worth considering this nuance when choosing food.

It is also worth noting that the normal performance of its functions by the amino acid in question is possible only if there is a sufficient amount of arginine in the body.

Therefore, it is optimal to choose fermented milk products rich in these two components for nutrition.

Main functions and benefits

Among the main functions and benefits that are associated with lysine are:

help in the absorption and accumulation of calcium;
the ability to metabolize fat and influence weight loss;
regulation of serotonin levels in the brain;
help in the formation of collagen, which affects the skin, bones, tendons and cartilage;
muscle building and tissue repair;
improving memory and concentration;

a decrease in LDL (low density lipoprotein) levels;
improving the synthesis of enzymes and hormones;
increased production of antibodies necessary to maintain immunity;
assistance in the recovery of the body after surgery or serious injuries.

Lysine-rich foods

You can fill the daily requirement for the amino acid in question with the following food products:

dairy and sour milk products -, hard cheese,;
meat - pork, lamb, chicken, turkey;
quail and;
fish - cod, sardine;
fruits - pear, apricots,;
vegetables - leafy (,), cauliflower, legumes, soy,.

Daily requirement and rate

The daily requirement of lysine for a person is 23 mg per kilogram of a person, so the rate per day is different for everyone and depends on weight and age.
For example, an adult who weighs 60 kg will need about 1.38 g of lysine per day.

Important!It is worth noting that during the period of active growth, young children should receive at least 170 mg per kilogram of weight into the body.

You also need to pay attention to the fact that there are some nuances when calculating the daily rate for a person:

If a person goes in for sports or his work is associated with constant physical activity, then the amount of an important component should be increased by 30-50%.
As men age, they need to take higher doses to keep their bodies healthy. Increase your amino acid intake by 30%.
Vegetarians also need to rethink their diet, as animal proteins are not absorbed into the body. The same applies to people who are on low-fat diets.

About excess and lack

It has been proven that the human body needs lysine and suffers when its deficiency is recorded. But what happens when the consumption of foods containing the amino acid in question increases significantly and an excess is recorded in the body, let us consider in more detail.

Excess

An excess of amino acids in the human body can be recorded extremely rarely.

This is usually associated with unhealthy exhausting diets and nervous fatigue, in which case the component accumulates in the body in large quantities and in rare cases provokes a decrease in immunity and a tendency to viral diseases.

Again, this is most likely an exception, since lysine is well absorbed, and its excess is excreted in the urine.

a lack of

Lack of lysine is very dangerous, it is associated with the appearance of various problems, which are characterized by:

depressive state;
worsened mood;
herpes sores on the lips;
regular broken limbs;
weak bone tissue;
weight loss;
enlarged blood vessels in the eyeball;
poor stress resistance;
regular headaches;
poor hearing;
impaired growth of children;
baldness of the body;
problems with the regularity of menstruation;
poor appetite;
feeling unwell;
an increase in seasonal morbidity.

Interaction with other substances

Of course, lysine constantly interacts with substances that either come from the outside or are synthesized in the body.

Should be consideredthat the amino acid in question can significantly increase the toxicity of aminoglycosides.

In some cases, when interacting with antibiotics, allergies can be provoked, accompanied by diarrhea and nausea.

Do not get carried away with calcium-containing foods when enriching the diet with foods high in this component. Since in this case, an increase in nutrient can provoke the development of hypercalcemia.
Arginine significantly increases the amount of assimilated lysine.

To get the most out of your proteins, it's best to combine them with lysine, iron, bioflavonoids, vitamins A, B1, C.

Lysine in sports and sports nutrition

Lysine is an integral part of sports nutrition. It is actively used to feed bodybuilders, and is also added to sports nutrition and dietary supplements during their manufacture.

The following popular sports nutrition products are on the market, which contain a high concentration of an important amino acid:

L-Lysine 100 caps from NOW;
L-Lysine 100 caps from Twinlab;
L-Lysine 60 caps from IronMan.

Did you know?In the USSR, lysine was first obtained in 1964, at this time it began to be produced at a rapid pace and soon the Union became the third in the production of all world lysine.

The amino acid can help speed up muscle recovery after strength training. It is also effectively used for the successful modeling of the figure, since using this product, you can achieve good muscle growth.

The main functions of lysine in sports are protective and nutritional.

Thus, lysine is an integral part of the human body and performs vital functions. It is very important to add foods that are rich in this component to the diet, which will protect yourself from a lack of lysine and prevent the development of serious problems.

Lysine is a diaminohexanoic acid that plays an essential role in human life. L-Lysine (also called lysine) is an essential amino acid that has become very popular for its amazing health benefits. Lysine is found naturally in many protein-rich foods such as meat, fish, eggs and dairy products.

More and more people are using L-Lysine supplements because of their huge role in maintaining a healthy immune system, treating colds, and lowering cholesterol levels. Lysine helps manage stress, improves athletic performance and improves hair health.

The body cannot make lysine. The only way to get enough of this essential amino acid is through a nutritious diet. However, many vegetarians cannot get enough lysine because cereals have low levels of protein containing lysine. In addition, some cooking methods reduce the lysine content of the final meal.

While lysine is generally safe to use as a dietary supplement, it can have some side effects on the digestive system. Especially if you neglect the norms and take too much.

Some of the side reactions of lysine are abdominal pain, diarrhea, and nausea. However, no major safety issues have been reported from clinical trials. Supplements are recommended for widespread use.

This article looks at the main health benefits of L-lysine and the role this essential amino acid plays in building a strong immune system and a healthy body.

What is L-Lysine (Lysine)?

L-Lysine is one of 9 essential amino acids that the body needs for growth, tissue repair, and other bodily functions. Lysine is the same amino acid, without which the formation of carnitine, collagen and calcium absorption is practically impossible. Essential amino acids such as lysine must be obtained from food or supplements to provide the body with adequate protein and energy.

For medical reasons, lysine can be dosed from 1 to 3 grams per day; in this range, the amino acid is absolutely safe for use in adults. A higher dose may be used in cases of herpes simplex breakouts.

In general, the instructions for use recommend taking lysine on an empty stomach, 30–35 minutes before meals. If you have eaten, then it is better to take the supplement after waiting about 2 hours. If it is a pill supplement, then the daily allowance is prescribed as 1000 mg. For patients with bone and cartilage tissue damage, the daily rate doubles.

In simple words, 1 tablet 1 to 3 times a day between meals. During the period of remission of herpes infection - 1250 mg daily. With relapses - 2,000 - 3,000 mg / day. For intense training, the recommendation is approximately 12 mg per kilogram of weight.

Do not be afraid of long-term use of L-Lysine supplements. The amino acid does not accumulate and does not have a toxic effect on humans. Lysine plays the role of a source of energy, and any excess is excreted during urination.

Lysine deficiency symptoms

Loss of appetite;
Excessive hair loss;
Hyperstimulation, lack of attention;
Fatigue;
Stress, mood swings;
Bloodshot eyes;
Stones in the kidneys;
Anemia;
Growth retardation;
Nausea, dizziness;
Reproductive Disorders.

Lysine requirements and dosages

Infant (3-4 months): 103 mg / kg per day
Children (2 years): 64 mg / kg per day
School-age children: 58 mg / kg per day
Adults: 30 - 35 mg / kg per day

Lysine intake in a typical diet is 40-180 mg / kg per day, with the upper limit being 300-400 mg / kg per day.

Some patients may require chronic use at higher doses. For example, patients with herpes can take up to 9 grams per day, especially during flare-ups.

Foods that contain L-lysine

With the right diet, you can get enough lysine daily. However, since the main food sources for lysine are meat and dairy products, this may not be true for everyone.

According to the Institute of Nutrition, here is a list of the best foods that contain the amino acid lysine:

A hen.
Turkey.
Fish, including tuna, cod and pike.
Beef product.
Pork.
Game meat.
All the milk.

Other foods that contain lysine are cheeses, eggs, nuts, seeds, and legumes.

Scientifically Proven Health Benefits of L-Lysine

Let's now take a look at how lysine helps maintain health and how L-lysine supplements can be used to enhance your health. Knowledge will come in handy if you suffer from herpes, acne, shingles and need to improve athletic performance.

1.L-lysine in foods can help heal herpes

L-Lysine is one of the best supplements for treating colds. Herpes, always untimely, is caused by the herpes simplex virus type 1 (HSV-1). This virus causes small, painful blisters to form around the mouth. The bubbles fill with fluid, burst, resulting in painful sores on the face.

Research has shown that L-lysine helps to heal the HSV-1 virus, and most importantly, herpes is treated naturally. The experimental group showed that within 3 days, L-lysine completely cured herpes symptoms in 40% of the participants. Nearly 90% of them found that within 6 days they had no more herpes symptoms.

Lysine cream can be used for this purpose. It is enough during the day and especially at night to apply the cream to the ulcers to cure herpes and speed up the healing of symptoms.

With the herpes virus, it is very important to establish proper nutrition. The diet should be saturated with foods in which lysine predominates and arginine is practically absent.

For example, if you consume only 150-200 g of chicken products, then you can fully get the daily norm of lysine. If you put on fish or shrimp, then 200 g will be enough. You can saturate the body with lysine with ordinary milk. But for this you have to drink up to 5 glasses a day.

2. Supplementing L-lysine for the treatment of herpes virus

L-lysine supplements are also effective in treating herpes outbreaks. Herpes can also affect the genital area and cause blisters in intimate areas. Possible muscle pain and burning sensation when urinating.

They gave participants who had genital herpes, with blisters and sore sores, a dose of 1 gram of lysine supplementation per day. As a result, they found that lysine helped get rid of herpes blisters in less than 5 days. As a result, lysine is recognized as an "effective treatment for herpes infection."

A lysine-rich diet or 1 gram of L-lysine supplements daily can help prevent outbreaks of herpes virus infection and improve symptoms faster. Pay special attention to this in winter.

The beneficial properties of lysine and its effect on the body are not limited to helping with herpes. The addition of lysine to the diet becomes an excellent assistant in the fight against ARVI.

A number of other useful properties, tune our body to vital functions without depression. L-Lysine is credited with the ability to reduce anxiety and irritability. While taking lysine, migraine headaches noticeably decrease or completely disappear. Note that lysine does not cause drowsiness, does not affect performance, does not cause addiction.

3. Lysine helps treat shingles

L-Lysine also helps treat and prevent shingles. This painful skin condition is caused by the chickenpox virus and is associated with the herpes virus. Shingles causes a painful skin rash, itching and blistering. Lysine can help cells repair. Thus, L-lysine helps to treat the symptoms of a skin rash associated with severe pain.

The effectiveness of lysine in the treatment of herpes zoster was proven in a 2016 study. Studying the results of the work, lysine clusters were found in the regenerated skin cells. This proves that lysine helps prevent the spread of the virus.

In addition to taking L-lysine supplements to relieve herpes zoster symptoms, you can also use honey and clover. They are equally effective in treating an outbreak of herpes zoster. If you are looking for more effective ways to treat a disease, then try to resort to medications:

acyclovir 800 mg 5 times a day. Every 4 hours (not necessary at night) 7-10 days;
famciclovir 500-750 mg 3 times a day by mouth for 7 days;
paracetamol, diclofenac - if there is acute pain;
silver sulfadiazine - topical application if there is suppuration and rash;
idoxuridine - eye drops if the rash has developed around the eyelids.

4. L-lysine may enhance athletic performance

Together with the amino acid L-Arginine, L-Lysine may help improve athletic performance. Many athletes and gymnasts alike take L-Lysine and L-Arginine together to boost growth hormone levels. By the way, this helps the muscles recover faster after training.

The reason L-Lysine may improve athletic performance is because it converts fatty acids into energy and is an essential amino acid for faster muscle growth.

It is now absolutely known that when taking 1200 mg of L-lysine and 1200 mg of L-arginine, human growth hormones increase 8 times.

However, health professionals mention that high levels of arginine can lower lysine levels in the body, so talk to your doctor before taking L-lysine and L-arginine together.

5. L-Lysine May Help Reduce Acne Outbreaks

L-lysine supplements can help reduce the severity and frequency of acne outbreaks. Although no scientific studies have proven a direct link between the amino acid lysine and acne, many acne sufferers find lysine to be very beneficial.

The reason lysine may help some people with acne is because it helps the skin to repair itself. Lysine is fundamental in collagen formation. Fibrillar protein, which forms the basis of the body's connective tissue, is especially necessary to maintain elasticity and protect the skin from damage.

Does lysine help for acne? Can L-Lysine Supplement Get Rid of Acne? There will likely be improvements, but only if you were lysine deficient prior to taking the supplement.

A more promising method to get rid of acne is to increase collagen production. A person can independently synthesize the required amount of collagen by consuming healthy food. Lysine is designed to strengthen the collagen structure. By increasing the amount of lysine in the body, you can give the skin additional strength and density.

A decrease in collagen is observed already at the age of 25. Because of this, the first signs of skin aging appear. Certainly, additional lysine will become an ally in the struggle for youth.

6. Lysine fights hair loss

Make sure you have enough lysine in your diet. It is a natural and reliable way to reduce hair loss. Healthy hair needs amino acids to grow and be strong. Lysine deficiency is the first cause of hair loss in women.

Clinical and experimental dermatology states that women with low lysine levels suffer from hair loss. Research shows that taking L-lysine and iron supplements can effectively prevent and reverse the effects of thinning and hair loss.

There are many other supplements that can help combat hair loss and thinning. Some of them are biotin, vitamin D, and saw palmetto. You can also try natural methods for stimulating hair growth, such as:

peppermint essential oil;
squeeze of rosemary;

7. Lysine helps reduce anxiety and stress

Stress and anxiety can negatively affect our lives. While we may not always be able to address the root cause of stress, there are herbal supplements that can help you deal with stress faster. If you suffer from anxiety, L-Lysine supplements can be a natural remedy for better treatment of stress and chronic anxiety.

The combination of L-lysine with the amino acid L-arginine effectively reduces stress levels in healthy people. For extreme stressful situations, take 2,600 mg daily of both L-lysine and L-arginine. After a week, baseline stress and anxiety levels will decrease significantly.

In addition, L-lysine supplements can help increase the effectiveness of antidepressants such as diazepam. A set of measures can reduce anxiety by blocking stress response receptors.

Summary. Replenishing cell stores with lysine reduces anxiety and lowers cortisol levels - popularly called the stress hormone. The addition of L-lysine to the diet of patients with schizophrenia alleviates the symptoms of the disease.

8. Lysine can lower cholesterol levels

Using L-Lysine along with other natural ingredients can help lower blood cholesterol levels naturally.

If a man with high cholesterol is treated with L-lysine supplementation, he will most likely be able to curb his growth. When L-lysine is combined with garlic supplements, cholesterol levels are reduced by 25 points. Doctors confirm: - Lysine helps prevent the accumulation of cholesterol in the blood vessels.

Make sure you are rich in L-lysine and fiber. This is a great way to lower cholesterol levels and prevent negative processes in the heart muscle.

9. Lysine Reduces Some Complications of Type 2 Diabetes

Another undeniable benefit that L-lysine can boast of and improve your health is that it can prevent some of the symptoms associated with type 2 diabetes.

L-lysine has a positive effect on blood sugar levels and works together with other enzymes to prevent harmful reactions (such as glycation) in the blood.

L-Lysine has definitely been proven to prevent glycation. The amino acid researchers concluded that L-lysine is "an effective therapeutic supplement for type 2 diabetes and reduces the risk of infection in these patients."

10. Lysine in the prevention of Alzheimer's disease

There is some research that suggests that L-lysine may help prevent the development of Alzheimer's disease and prevent dementia.

Researchers have found that the HSV-1 virus is associated with dementia. This is most likely one of the factors contributing to the development of Alzheimer's disease.

At this time, there have not been enough clinical trials to establish a definite link between L-lysine supplementation and prevention of Alzheimer's disease. However, the researchers concluded their study by stating that "adequate doses of lysine can prevent the development of Alzheimer's disease."

L-lysine side effects

L-lysine supplements are considered safe to take, but you should always stick to the recommended dose. You should also remember that a proportion of lysine is present in many of the foods we eat. Therefore, if you look towards proper nutrition, you will not be deficient in L-lysine.

However, an overdose of L-lysine is possible, although very rare. The most common side effects of L-lysine have been observed to be:

Diarrhea;
Nausea;
Abdominal pain.

According to the Medical Health Center, L-lysine can increase calcium absorption. Care must be taken when taking large amounts of calcium if you are taking lysine supplements.

Also, excessive doses can cause the formation of gallstones. If you have liver and kidney problems, are pregnant, or are taking any medications, you should consult your doctor before purchasing and starting L-lysine supplements.

Where to Buy L-Lysine Supplements

L-lysine supplements are available at many health care stores, pharmacies, and health food centers. You can also buy the supplement at a bargain price in online stores.

L-Lysine - an essential amino acid, which is part of almost any protein, plays the role of a building material for all proteins, promotes the growth and restoration of collagen, participates in the production of antibodies, hormones and enzymes Lysine is obtained from fish, meat, dairy products, ovary of wheat, rye, fruits and vegetables; in plant products, the lysine content is almost always limited. Lack of lysine adversely affects protein synthesis, which leads to increased fatigue, poor appetite, weight loss, irritability, bleeding in the eyeball, hair loss, decreased libido and potency, and other problems in the reproductive sphere. With a deficiency in the body of lysine, the growth rate of children slows down, and early gray hair appears in adults.

At the end of the 20th century, scientists managed to discover the unusual properties of L-lysine, which allow this amino acid to actively fight the viruses that cause herpes and acute respiratory infections. Numerous studies have shown that lysine contributes to the lengthening of the recurrence interval in various types of herpes (including genital). After a herpes virus of any type first entered the body or at the time of an exacerbation, viruses begin to multiply. They use the amino acid arginine as a building material. L-lysine in its structure and chemical properties is identical to L-arginine and, when ingested in large quantities, lysine simply replaces arginine. The herpes virus cannot differentiate between them and begins to produce new viruses from lysine. But without arginine, the virus cannot multiply and the newly formed herpes viruses cannot continue to multiply and die. In order to prevent recurrence of herpes, it is necessary to use L-Lysine in sufficient quantities. As you know, relapses of herpes occur most often in stressful situations that weaken the body due to an increase in the level of steroid hormones under stress, which leads to the rapid consumption and depletion of L-lysine reserves in the body. Since L-lysine is involved in the production of antibodies and other cells of the immune system, the body is left without adequate immune protection, which leads to the recurrence of herpes.

The amino acids lysine and arginine, which compete with each other, when absorbed into the blood, become allies in strengthening the immune system. When taken simultaneously, the state of immunity is significantly improved, in particular, in health programs for AIDS, viral hepatitis and chronic fatigue syndrome, which is of a viral nature. Lysine restores the structure and improves the trophism of the nervous tissue and brain activity after an adverse effect on the nervous system of herpes viruses, accelerates the restoration of the integrity of the skin and mucous membranes after damage by viruses.

L-lysine improves the formation and secretion of important hormones of a protein nature - hormones of the thyroid gland, pancreas, pituitary gland, stimulates the active synthesis of growth hormone, helps to increase libido in women and potency in men. It also increases the enzymatic activity of the digestive tract, improves the digestion process, helps restore intestinal microflora, and is effective in long-term antibiotic treatment and in weight normalization programs. Lysine is a powerful source of energy, accelerates the breakdown of fat, promotes weight loss and mobilizes fat for energy needs.

It has been proven that lysine has a mild antidepressant effect, stimulates mental performance, increases energy potential, relieves migraine-type headaches, increases libido in women and stabilizes erectile function in men. Scientific experiments have shown that with prolonged use of lysine, a decrease in concentration and performance, mental or physical dependence, improves memory. Lack of lysine in the diet can cause increased fatigue, nausea, dizziness, lethargy, decreased appetite, nervousness, and menstrual dysfunction.

Lysine is a precursor to the amino acid carnitine, which is essential for heart health and cardiovascular health. Lysine helps to reduce the level of low-density cholesterol in the blood, preventing it from settling on the walls of blood vessels and protecting against atherosclerosis and related diseases - hypertension, coronary heart disease, circulatory disorders of the brain, heart and all internal organs.

There is a correlation between lysine deficiency and calcium deficiency in bone tissue. Lysine is necessary for normal bone formation and growth in children, participates in the synthesis and formation of collagen to repair damaged tissues, improves the absorption of calcium from the blood and its transport to bone tissue, therefore it is successfully used for the prevention and treatment of osteoporosis. All postmenopausal women need to take lysine, it is necessary for the absorption of calcium from food and its incorporation into bone tissue, and with a deficiency of lysine, the excretion of calcium in the urine increases.

Lysine improves vision, prevents the development of cataracts and other degenerative processes of eye tissues, it slows down the process of destruction of the tissues of the lens of the eye under the influence of high blood sugar, therefore, in diabetes mellitus of both type 1 and type 2, it is necessary to take lysine to provide additional protection from cataracts. Lysine significantly strengthens nails, improves and thickens hair structure and skin condition, scientists associate this role of L-lysine with its effect on improving the absorption of iron and zinc.

L-Lysine maintains a positive nitrogen balance by creating an anabolic environment in the body, takes part in the formation of muscle proteins, helps to increase muscle volume and muscle strength, and participates in collagen formation and tissue repair during exercise. Lysine. Athletes use L-Lysine to build muscle mass, to recover from sports injuries, and to treat fatigue and overtraining.

Results of clinical studies LYSINA

Lysine in Virology

Herpetic infection is one of the most common infectious diseases with an uncontrollable epidemic process. Herpes belongs to the category of opportunistic infections that manifest themselves when an immunodeficiency condition occurs, at the same time, with a recurrent course, herpes viruses are an independent factor that aggravates immunodeficiency and, as a result, a vicious circle of herpes infection is formed.

Currently, more than 100 types of herpes viruses have been described, of which the first 3 types have the greatest prevalence and clinical significance: herpes simplex viruses of types 1 and 2 - causative agents of herpes simplex of the skin and mucous membranes, ophthalmic herpes, genital herpes, neuroherpes in newborns and herpes of type 3 - virus Varicella-Zoster, the causative agent of herpes zoster and chickenpox. Herpetic infection has various clinical manifestations, which often leads to incorrect diagnosis and subsequent treatment of the pathology of various organs, and not the infection itself.

The main goal of the treatment of recurrent herpes infection is to lengthen the intervals between relapses, weaken the clinical severity of exacerbations, and prevent transmission of infection to relatives, sexual partners or newborns. Despite the seeming simplicity of the task, in practice it is difficult to reduce the number of relapses during the year conceived. Dissatisfaction with the therapeutic potential of existing treatment regimens leads to the search for both new drugs and approaches to treatment.

A number of studies around the world are devoted to the study of the action of L-lysine, their results were published in 1978 in the journal Dermatology, in 1981 in the journal Chemotherapy and in 1983 in the Journal of Antimicrobial Chemotherapy. Studies by a number of virologists have revealed that L-lysine is able to inhibit the replication of the herpes simplex virus in cells and thereby shorten the duration of the disease. In clinical studies, the use of lysine has been effective in reducing the symptoms of facial and herpes zoster. At the same time, in 40% of patients the complete disappearance of these symptoms occurred on the 3rd day and in 87% - by the end of the 6th day of treatment, while the clinical manifestation of the disease in the absence of adequate therapy lasts 21 days.

It has been found that lysine stimulates immunity, makes a person more resistant to diseases and helps to cope with existing diseases, has an effective antiviral effect in herpes and acute respiratory infections, which makes it indispensable in immunodeficiency states. It was also found that viral reproduction is suppressed by the intake of lysine with a simultaneous deficiency of arginine. When treating herpes, a diet high in lysine and a minimum of arginine should be followed and supplemented with lysine. The dose of lysine to prevent relapse of the disease should be 1250 mg daily on an empty stomach.

Conclusion:Thus, the above materials make it possible to consider L-lysine as a substance with pronounced antiviral activity. As an adjunct to the standard drug package, L-lysine 1000 mg orally is used in the treatment of genital herpes.

Lysine in immunology

Adequate supply of the body with the necessary amino acids is a prerequisite for the normal functioning of the immune system. Especially important is the normal intake of two amino acids - lysine and arginine. These amino acids are essential for the production of a sufficient number of neutrophils, which are part of the body's strategic defense system against hepatitis, HIV infection, chronic fatigue syndrome and any immunodeficiency conditions. Studies in animals have shown that a lack of lysine causes immunodeficiency conditions. Lysine increases and normalizes the number of lymphocytes both in percentage and in absolute terms, increases the globulin fraction of blood protein and the amount of total protein and thus has a pronounced immune-correcting effect, increases the body's defenses, prevents the development of inflammatory complications.

You also need proper nutrition - the key to good health and excellent functioning of the immune system. Modern scientific evidence suggests that a number of foods can provoke a weakening of the immune system: fatty foods rich in cholesterol, sugar and alcohol are another cause of frequent herpes flare-ups. Cholesterol reduces the formation of leukocytes - the main cells of the immune system, sugar slows down the absorption of vitamins B and C in the intestine, which leads to a decrease in immunity, alcohol has a direct toxic effect on immune cells.

Conclusion: Lysine increases the body's resistance to infections, stimulates the production of interferon, antibodies and phagocytosis - the absorption of viral particles by the cells of the immune system, therefore, lysine always participates in programs for the comprehensive improvement of the body in viral infections of the liver, respiratory and genitourinary systems.

Lysine in neurosurgery

Brain injuries and their consequences remain one of the most difficult and unsolved problems of modern medicine and are of great importance due to their prevalence and severe medical and. social consequences. As a rule, a significant increase in the number of persons with head injuries is observed during periods of war and the years following them. However, even in conditions of peaceful life, due to the growth of the technical level of development of society, a fairly high injury rate is observed. According to a study of traumatic brain injury carried out in the early 1990s, over 1 million 200 thousand people annually receive only brain damage in Russia. In the structure of disability and causes of death, craniocerebral injuries and their consequences have occupied the second place after cardiovascular pathology for a long time.

On the basis of the Institute of Neurosurgery of the Academy of Medical Sciences of the Ukrainian Scientific Research Institute of Traumatology and Orthopedics, studies have been carried out on the use of L-lysine in traumatic brain lesions. According to the study, already on the 3-5th day from the start of treatment with the drug, there is a significant decrease in the area of \u200b\u200bedema around the foci of bleeding and the intensity of the area of \u200b\u200bedema, the size of the foci of contusion decreases, small foci of contusion up to 10-15 mm have completely resolved. In patients in whom drug treatment began in the first hours after the injury, cerebral edema around the contusion foci did not develop at all. The size and density of bleeding in the bruised focus clearly decreased. In patients with traumatic cerebral edema, lysine eliminates the severity of edema, compression and displacement of brain structures, promotes resorption of contusion foci, including their hemorrhagic component, and eliminates intracranial hypertension.

Conclusion: L-lysine is recommended for clinical use for the prevention and treatment of traumatic edema of the brain, soft tissues of the skull, face, trunk, extremities at the prehospital and hospital stages of treatment of patients with isolated and concomitant traumatic brain injury.

Lysine in cardiology

Diseases of the cardiovascular system occupy one of the first places among diseases of internal organs, they are often the cause of disability and premature death. Heart attacks are the leading cause of death today, but their role in early mortality is often underestimated, since these diseases are more common in older people; nevertheless, myocardial infarction increasingly affects people under the age of 40 and in 45% of cases occurs in people under the age of 65. In the United States, 966,000 people died from cardiovascular diseases in 1987 - almost the same number as from cancer, AIDS, pneumonia, flu and accidents. In Russia, up to 1.2 million people die from heart disease every year. Heart disease has long been considered predominantly "male", but today doctors are faced with an increase in the number of cardiovascular diseases in women. This became possible because in our time the main risk factors that traditionally provoke the development of heart attack and stroke are equally inherent in both men and women. Most often, this is an unhealthy diet, leading to obesity and the development of atherosclerosis, smoking (including passive smoking), alcohol abuse, a sedentary lifestyle, hereditary diseases.

Most diseases of the cardiovascular system begin with atherosclerosis - with the gradual "clogging" of blood vessels, when the arteries lose their elasticity, and their lumen narrows as a result of the deposition of cholesterol on the inner surface of the vessels.
In 1996, Matthias Rath, an internationally renowned German scientist and physician, led a team of researchers that made a breakthrough in cell medicine that saved the lives of millions. Studies have clinically proven that in early atherosclerosis, increased intake of lysine in combination with a complex of vitamins, macro- and microelements and antioxidants slows down the development of atherosclerosis by an average of 50%, and in some cases leads to a complete regression of atherosclerotic deposits. Research by Dr. Matthias Rata confirmed that lysine blocks the action of lipoproteins - complex protein-fat complexes that are part of all living organisms and are a necessary component of cellular structures. Some low-density lipoproteins lead to blockage of the arteries and the development of atherosclerosis, and lysine intercepts them and prevents them from being deposited on the walls of the arteries.

Conclusion: Lysine prevents the formation of lipoproteins that cause blockage of the arteries, therefore, it will be useful in cardiovascular diseases, including high blood pressure, which is one of the main causes of heart attacks and strokes.

Lysine in oncology

Tumor metastasis is the most important indicator of the malignancy of the tumor process, which determines the course of the disease and the fate of the patient. The vast majority of tumors metastasize to the lymph nodes; in the later stages of the disease, metastases are found in the lungs, liver, bones and other organs. In some cases of malignant tumors, distant metastases develop with a small size of the primary tumor, sometimes not yet captured by research methods. In some cases, metastases are found only a few years after radical surgery for cancer of the breast, colon, etc. Great importance in the enhancement of metastasis is attributed to the violation or weakening of the protective immunobiological mechanisms of the patient's body.

Research carried out in 2002 showed that lysine inhibits the action of collagenases, enzymes that dissolve the membranes of cancerous tumors, and that the membrane of tumors inhibits the metastasis of cancer cells of various types. The successful use of lysine for the treatment of breast and ovarian cancer was reported by the research team of Dr. Asted (University of Lund, Sweden) in 1977. In 1980, Dr. Suma from Tokyo reported on the treatment of inoperable ovarian cancer with metastases to the abdominal cavity. And in this case, the process was stopped and during three years of follow-up, no relapses occurred.

Conclusion:Since the biological mechanism of metastasis is the same for all types of cancer, the use of lysine in combination with other similar substances can inhibit or completely block the spread of cancer of all types studied, and it is assumed that AIDS is also.

Lysine in endocrinology

The value of growth hormone for humans is difficult to overestimate, it is produced in the anterior lobe of the pituitary gland, regulates the metabolism of proteins, carbohydrates and lipids, this hormone contains 191 amino acids. Growth hormone in the human body is responsible for the growth of bones and tissues, for the increase in body length and the growth of internal organs. From birth to 20-25 years of age, its greatest productivity is observed, a lack of hormone in childhood and adolescence leads to dwarfism, delayed sexual development, loss of hair and mental retardation. By the age of 30, the production of growth hormone slows down and stops at approximately the same level, in connection with which the still invisible aging processes begin, a slight decrease in immunity is observed. After 40-45 years, the pituitary gland produces 50% less growth hormone compared to previous years. The signs of physiological aging of the body become more pronounced, the quality of sleep decreases, appetite is disturbed, and extra pounds appear.

In 1981, Doctor of Medicine A. Isidori at the University of Rome Clinic conducted research on young men aged 15 to 20 years, receiving simultaneously two amino acids - arginine and lysine. At the beginning and at the end of the study, the level of growth hormone was measured in all subjects. In a group of 15 male volunteers, a study was conducted to assess the rate of release of growth hormone after stimulation with amino acids. The result confirmed the stimulation of the production of growth hormone and insulin as a result of oral intake of a combination of two amino acids - L-lysine and L-arginine.

Conclusion: The combination of lysine + arginine has been proven to promote growth hormone release ten times more than arginine alone. Growth hormone has biological activity, which is confirmed by radioreceptor analysis, this effect is specific to the combination of these amino acids, none of them, taken separately, produces such an effect.

Dietary supplement L-LYSINE MONOHYDROCHLORIDE company Nutricare recommended:

* For the prevention and rehabilitation of immunodeficiency states (viral and infectious diseases, hepatitis, herpes types 1 and 2, HIV infection),

* For the prevention and recovery of cardiovascular diseases(ischemic heart disease, atherosclerosis),

* For the prevention and rehabilitation of diseases of the nervous system (depression, anxiety, neurosis, frequent stress),

* For the prevention of premature aging (osteoporosis, baldness, cataracts, climacteric syndrome, decreased libido and potency, recovery from illness),

* For the prevention and recovery of endocrine disorders(diabetes mellitus, hypothyroidism, obesity),

* For the prevention and improvement of chronic fatigue syndrome (weakness, lethargy, apathy),

* When playing sports (high loads, fatigue, sports injuries, symptoms of overtraining),

* And also in case of eye diseases.

Usage: 2 tablets with meals 1 time per day

L-Lysine (L-Lysine)

Beneficial features:

Formation of carnitine, which is responsible for the condition of hair and skin;

Collagen synthesis to help avoid wrinkles;

Reducing cholesterol levels;

Improving the absorption of calcium.

Lysine Is an essential amino acid that cannot be synthesized by the body and only enters the body with food and supplements. Lysine has a wide range of biological effects and, above all, lysine is vital as a component of body proteins. This amino acid is found in large quantities in collagen, which provides strength to muscles, cartilage, ligaments and tendons. Indirectly, lysine strengthens bones, as it promotes the absorption of calcium from the intestines, with a lack of it, osteoporosis (increased fragility of bones) can develop. Lysine plays an important role in the immune system as it is required in large quantities for the production of antibodies (immunoglobulin). Lysine is part of hormones and enzymes that regulate the body's metabolic processes.

Some studies have shown that l-lysine can reduce the incidence of the herpes virus.

The way the substance affects the herpes virus is unknown, but there is a version that lysine affects another amino acid - arginine. In turn, the effect of arginine on the acceleration of cell division in infected with the herpes virus was established. The less arginine, the slower herpes develops, and l-lysine reduces the activity of arginine.

In 2007, an account from the University of Florida (FSU) found the effect of "lysine conjugates" to identify individual DNA lesions. The research was carried out by Igor Alabugin, professor of biochemistry at FSU. For the treatment of cancer, it has been proposed to use lysine conjugates under the influence of phototherapy. Such a complex effect allows you to destroy 90% + of diseased cells, while not damaging healthy ones. The invention of Professor Alabugin has already been patented and is being tested.

The use of lysine to treat cancer was tested in mice in colorectal cancer in 2014. During the study, 0 animals died, including animals that were in the advanced stages of the disease.

Studies have shown the effective effect of l-lysine even on such types of diseases as leukemia, which gives rise to additional hope for the speedy deliverance of mankind from such a terrible disease.

Along with eating foods rich in B vitamins, magnesium and omega-3, l-lysine can be taken to treat psychological problems. Lysine improves the absorption of calcium and other substances, thereby restoring the normal state of the body. This amino acid is used to relieve anxiety syndrome and can relieve depression harmlessly for the body.

L-lysine acts as a serotonin receptor antagonist. It binds to receptors and partially prevents feelings of anxiety. Moreover, the substance affects stress-induced responses, including the treatment of diarrhea.

L-lysine supplementation has been linked to improved calcium absorption, which is extremely important for people at risk of developing osteoporosis. To date, there are no studies that support a link between osteoporosis treatment and lysine intake, but the importance of calcium's effects on bone health suggests that lysine may be beneficial.

Calcium affects not only your bones, but also affects your weight, protects against serious diseases, reduces PMS symptoms, improves dental health, affects the functioning of the nervous system and muscles, and prevents diabetes.

Most of the inhabitants of our planet experience problems related to gut health. Many people are not even aware of these problems, but they have a significant impact on their health. It's not just about direct problems like acid reflux or diarrhea, but many others. For example, a violation of the intestinal microflora can affect the condition of the skin, hair and bones, due to the fact that the necessary substances are not absorbed by the body.

One form of l-lysine known as poly-l-lysine has anti-inflammatory effects and relieves many gut problems.

American scientists have gone far, experimenting with lysine, their experiments have proven that the use of lysine can stop hair loss in androgenic alopecia and iron deficiency anemia. There is a US patent for the use of Lysine in the treatment of various hair loss problems, including baldness. Lysine blocks 5-alpha reductase. Lysine deficiency adversely affects protein synthesis, which leads to fatigue, fatigue and weakness, poor appetite.

Lysine is widely used in bodybuilding, it is added to sports nutrition and dietary supplements. This amino acid can help speed up muscle recovery after strength training. The modulating effect of lysine supports positive nitrogen metabolism and the building of muscle proteins.

Muscle protection and nutrition are the two main functions of lysine in sports. In addition, lysine strengthens the tendon corset and skeletal system, which reduces the risk of injury, and also speeds up recovery.

The average person needs to get 800 to 3000 mg of l-lysine daily. The dosage for the treatment of herpes can increase from 1 to 3 grams of the substance.

Lysine can be used as a cream to speed up the relief of herpes symptoms.

Literature
1. Ronald Klatz, Robert Goldman "The era of youth (Anti-aging revolution), published by Moscow, St. Petersburg," Ost ", 2007
2. US Patent No. 5678617.

Lysine

Are common
Lysine



Systematic name	2,6-diaminohexanoic acid
Abbreviations	Liz, Lys, K AAA, AAG
Chemical formula	HO 2 CCH (NH 2) (CH 2) 4 NH 2
Empirical formula	C 6 H 14 N 2 O 2
Physical properties
Molar mass	146.19 g / mol
Thermal properties
Classification
SMILES	C (CCN) CC (C (\u003d O) O) N

Lysine (2,6-diaminohexanoic acid) - aliphatic amino acid with pronounced base properties; essential amino acid.

Chemical formula: C 6 H 14 N 2 O 2

Lysine is an essential amino acid that is part of almost any protein, it is necessary for growth, tissue repair, production of antibodies, hormones, enzymes, and albumin.

Medications: Cardonate (contains 50 mg of lysine).

This amino acid has antiviral effects, especially against viruses that cause herpes and acute respiratory infections.

Studies in animals have shown that a lack of lysine causes immunodeficiency conditions.

Lysine maintains energy levels and keeps the heart healthy, thanks to the carnitine that the body produces from it. Studies have shown that a single dose of 5000 mg of lysine increases carnitine levels by 6 times. For this, vitamins C, thiamine (B1) and iron must be present in sufficient quantities.

Lysine is involved in collagen formation and tissue repair. It is used in the recovery period after surgery and sports injuries.

The combined intake of lysine and arginine (1-2 g per day) increases the body's immune response, in particular, the number and activity of neutrophils. Lysine enhances the action of arginine.

Synthetic lysine is used for enrichment of feed and food products.

Notes

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Synonyms:

See what "Lysine" is in other dictionaries:

LYSINE 20% - Bioconcentrate Composition. Lysine 20%; filler up to 100%. Act. Lysine, together with methionine and tryptophan, is an essential amino acid in pig and poultry feed. It is necessary for the assimilation of plant proteins, and it itself is involved ... Imported veterinary drugs

CH2 (NH2) (CH2) 3CH (NH2) COOH, an aliphatic amino acid with pronounced base properties. Part of proteins. An essential amino acid. Synthetic lysine is used to fortify feed and food ... Big Encyclopedic Dictionary

LYSINE - LYSINE, a, s diaminocaproic acid: HaN. CH2. CH2. CH2. CH2. CH (NH2). UNO; natural d lysine [a] fj ° \u003d + 14 ° to 15.5 ° for 2 5% hydrochloric acid solution. Free L. is not obtained in crystalline form. He's easy ... ... Great medical encyclopedia

- (H2N (CH2) .4CH (NH2) .COOH), a soluble ether AMINO ACID contained in proteins ... Scientific and technical encyclopedic dictionary

- (abbreviated Lys, Liz), L a, g diaminocaproic acid, an essential amino acid. It is a part of almost all animal proteins, grows, and microbial origin (in a large amount it is contained in histones and protamines, in a small amount in cereal proteins), participates in ... ... Biological encyclopedic dictionary

Diaminomonocarboxylic acid, an essential amino acid. It is part of almost all proteins, including microbial ones. The limited content of L. in proteins of vegetable origin significantly reduces their nutritional and feed value. For ... ... Microbiology Dictionary

Sush., Number of synonyms: 1 amino acid (36) ASIS Synonym Dictionary. V.N. Trishin. 2013 ... Synonym dictionary

lysine - a, m. lysine, it. Lysin c. lysis dissolution chem., biol. One of the amino acids found in almost all proteins. Krysin 1998. Lex. SIS 1954: lysins ... Historical Dictionary of Russian Gallicisms

lysine - Amino Acid Biotechnology Topics EN lysine ... Technical translator's guide

CH2 (NH2) (CH2) 3CH (NH2) COOH, an aliphatic amino acid with pronounced base properties. Part of proteins. An essential amino acid. Synthetic lysine is used for enrichment of feed and food products. * * * LYSINE LYSINE, ... ... encyclopedic Dictionary