Suppositories Kipferon for children: instructions for use and dosage for different ages. Kipferon candles: instructions for use and reviews Kipferon against influenza

Kipferon is a drug with immunomodulatory, antiviral, anti-inflammatory, anti-Chlamydial and antibacterial effects.

Release form and composition

Dosage forms - suppositories for vaginal or rectal use (5 pcs. In contoured cell packs, 2 packs in a cardboard box; 10 pcs. In a contoured cell pack, 1 pack in a cardboard box).

Active substances:

• Human recombinant interferon alpha-2 - 500 thousand IU;
• Complex immunoglobulin preparation (CIP) - 60 mg.

Auxiliary components: paraffin, fat, T-2 emulsifier.

Pharmacological properties

Pharmacodynamics

Kipferon is a drug containing human recombinant interferon alpha-2 and a complex of immunoglobulins.

The pharmacological characteristics of Kipferon are determined by the properties of its constituent components:

• Interferon alpha-2: activator of innate / acquired immunity with pronounced antiviral activity, increases resistance to chlamydial, mycoplasma, viral and bacterial infections; due to its immunomodulatory effect during immunological reactions, it promotes the growth and preservation of intestinal and vaginal normal flora. The biological activity of interferon alpha-2 is realized by its interaction with the receptor apparatus of immunocompetent and other cells, leading to an increase in the expression of HLAI and HLAII molecules on the surface of all types of cells, and regulation of cell cooperation, an increase in the activity of natural killer cells, as well as the communication of intact cells with resistance to cytolytic action, proliferation of CD8 T cells. Interferon alpha-2 increases the production of interferon gamma by natural killer cells;
• KIP (complex immunoglobulin preparation): contains specific and non-specific immunoglobulins of classes A, G and M, (IgA, IgG and IgM). The combination of antiviral, antibacterial, antitoxic and antichlamydia antibodies belonging to different classes of immunoglobulins provides agglutination, neutralization and precipitation of etiotropic pathogenic agents. At the site of application, it stabilizes interferon from secretions of mucous membranes, normalizes local immunity due to the intake of IgA and IgM with suppositories (replacement effect), increases the activity of locally formed cytokines.

Indications for use

• Frequent inflammatory diseases of the respiratory tract, pneumonia, recurrent bronchitis (including with obstructive syndrome);
• Viral hepatitis A, B and C in children;
• Viral and bacterial (coli-infection, dysentery, salmonellosis) intestinal infections, herpes, nonspecific inflammatory diseases in adults and children;
• Dysbacteriosis of the vagina and intestines of various origins;
• Urogenital chlamydia in women (including with manifestations of vulvovaginitis, vaginal dysbiosis, cervical erosion, cervicitis) against the background of conventional antibiotic therapy;
• Preparation for planned gynecological and other operations (in order to prevent infectious complications).

Contraindications

• Pregnancy;
• Lactation;
• Individual intolerance to the components of the drug.

Instructions for the use of Kipferon: method and dosage

Suppositories Kipferon are administered intravaginally (before contact with the posterior fornix of the vagina and the cervix) or rectally, 1-2 pcs. 1-2 times a day.

Kipferon can be used as the only etiopathogenetic treatment (without antibiotics) against the background of conventional basic therapy, including dosed nutritional therapy, oral rehydration and, if necessary, infusion therapy. In a severe course of the disease, it is advisable to include antibacterial agents in the complex of therapy.

The duration of treatment is on average 10 days. With erosion of the cervix, therapy is continued until the epithelialization of the erosion. If necessary, repeat the course.

Before intravaginal administration of the suppository, mucus should be removed from the mucous membrane of the vagina and cervix using a tampon. It is recommended to start treatment in the first days after the end of menstruation.

The use of Kipferon for chlamydial infections:

• Children: 1 suppository per day for 10 days. In girls with erased clinical forms of chlamydial vulvovaginitis without respiratory chlamydia, chlamydial urinary tract infection and clinical manifestations of the inflammatory process of the uterus and its appendages, treatment is carried out in combination with vaginal and oral eubiotics, in other cases Kipferon is combined with antibiotics and eubiotics;
• Adults: 2-4 suppositories per day, divided into 2 doses, for 10-14 days. The drug is used in combination with antibiotics, vaginal and oral administration of eubiotics. If, after the end of therapy, infection with chlamydia or clinical signs of chlamydia persist, a second course of treatment is prescribed.

For viral hepatitis A, B and C in children, Kipferon is used rectally. Recommended doses depending on the age of the child:

• Over 12 years old: 4 suppositories per day;
• 8-11 years old: 3 suppositories per day;
• Up to 7 years: 500 thousand IU / kg in 2 applications, but not more than 2 suppositories per day.

The duration of treatment in the acute course of the disease is 14 days. The first 7 days, the drug should be used daily, then 2 times a week. With a protracted course of hepatitis, the duration of treatment can be increased to 3-4 weeks.

• Adults: 2-4 suppositories per day for 10-14 days, if necessary, repeat the course of treatment;
• Children: 1 suppository 1 time per day for 10 days.

In case of concomitant bacterial infection, antibiotics are additionally prescribed. For women and adolescent girls, it is recommended to start treatment in the first days after the end of menstruation.

With frequent inflammatory diseases of the respiratory tract, pneumonia and recurrent bronchitis in children, Kipferon is used rectally 1 suppository 2 times a day during the first 5 days of treatment, during the next 3 weeks - 2 times a week. If necessary, the drug can be used as part of basic antibacterial therapy.

For intestinal infections, Kipferon is prescribed for children to be used rectally. The suppository should be administered after a natural act of defecation or a cleansing enema. Recommended doses depending on the age of the child:

• Up to 12 years: in a single dose of 50 thousand IU / kg, but not more than 1 million IU (2 suppositories) per day;
• Over 12 years: up to 2 million IU (4 suppositories) per day.

In preparation for planned gynecological and other operations, Kipferon is applied rectally 1 suppository 2 times a day (with an interval of 12 hours) for 3-5 days before the operation, during and in the postoperative period. The general course of preventive treatment is 10-15 days.

Side effects

Not identified.

Overdose

Cases of Kipferon overdose are unknown.

special instructions

Before use, you should consult your doctor.

Influence on the ability to drive vehicles and complex mechanisms

Application during pregnancy and lactation

It is contraindicated to use Kipferon during pregnancy and lactation.

Childhood use

In pediatric practice, it is allowed to prescribe Kipferon for children from the first days of life according to indications according to the dosage regimen.

Drug interactions

Kipferon can be used simultaneously with antibacterial drugs and eubiotics.

There is no information on interactions with other medicinal products.

Analogs

Kipferon's analogs are: Altevir, Reaferon-EC-Lipint, Reaferon-EC, Viferon.

Terms and conditions of storage

Store at 2-8 ° C in a place protected from light and moisture.

Expiration date - 1 year.

Application features

The drug under the trade name Kipferon is intended for administration by the rectal / vaginal method. One package contains 10 suppositories. The list of indications for use is wide and includes the following categories:

• diseases of the mouth and pharynx of an inflammatory nature of viral and bacterial etiology;
• respiratory diseases in acute form;
• urogenital chlamydia, accompanied by erosion, vaginal dysbiosis, vulvovaginitis, cervicitis;
• intestinal infections in an acute form of a viral and bacterial nature;
• violation of intestinal microflora in childhood.

The medication is approved for the treatment of children with hepatitis, as well as patients before surgery.

Often, doctors and patients use Kipferon substitutes. In the treatment of children, the most accessible and effective are Genferon and Genferon Light, as well as Viferon suppositories. For the administration of drugs, the rectal method is indicated. Suspensions, powders and tablets can also be used. The leading positions are occupied by Immunal, Anaferon, Bronchomunal, Ergoferon, Derinat, Ingaron, Irs-19. These immunomodulating and antiviral agents should be prescribed only by the attending physician, they have different dosages and methods of administration.

In the treatment of adult patients, Kipferon can be replaced with immunomodulatory medications with the trade names Oscillococcinum, Trekrezan, Isoprinosin, Polyoxidonium, Likopid. Most of these drugs are prohibited for the treatment of young children.

In the case of the treatment of diseases of the female genital area, the best analogue is Tantum Rose. This is a solution and powder for the preparation of a suspension, which are administered by the vaginal method. It has a powerful anti-inflammatory effect.

Review of analogues

The only complete analogue of Kipferon is Tantum Rose. Other drugs contain a similar component, interferon, but are incomplete substitutes.

Any pharmacy has on sale the presented analogs, but their use requires a doctor's prescription and the development of a therapeutic regimen.

Cheap substitutes for Kipferon

The original drug may be cheaper or more expensive than its counterpart. Not all patients are ready to buy a drug at a high price and choose a cheap substitute. When choosing, it is worth considering the age of the patient, his condition and disease. Only a doctor can select a medication with accuracy and develop a treatment.

Kipferon candles have the following cheaper analogs:

• Derinat - 400 - 500 rubles;
• Viferon - 200-300 rubles;
• Bronchomunal - 500-600 rubles;
• Genferon - 250-350 rubles.

When replacing the original with an analogue, keep in mind that most substitutes are less effective. The content of interferon is reduced in them and there is no second active substance, as in Kipferon.

Kipferon suppositories for the treatment of children can be replaced with a cheaper analogue Viferon. It is an antiviral drug prescribed for infectious and inflammatory diseases, viral hepatitis and acute respiratory viruses. It can be used in the treatment of newborn babies and when the baby is premature and has been diagnosed with an intrauterine infection.

To combat the problems of the genitourinary system in adult patients, including HPV (papilloma), the vaginal / rectal suppositories Genferon or its lighter form with the addition of Light are prescribed.

An analogue of Gerpferon is well suited to suppress the activity of herpesvirus infection.

Inflammatory processes and viruses in the genitourinary system in women are allowed to be treated with Viferon.

During colds, it is optimal to replace Kipferon with Giaferon.

Advantages and disadvantages

Kipferon suppositories, according to the instructions for use, have an advantage - its composition contains human recombinant interferon. This substance is responsible for the normal functioning of the human immune system. The medicine has a wide range of uses. It affects specific enzymes, which allows you to suppress the virus and stop its spread in the cells of the human body. The drug has persistent antibacterial properties, inhibiting the activity of pathogenic bacteria.

The use of Kipferon suppository allows you to relieve inflammation, eliminate infection, and increase the defenses of the immune system. Each consumer review is a confirmation of the effectiveness of the drug.

The main disadvantage is the high cost.

Contraindications and side effects

Kipferon candles, according to the instructions for use, unlike their counterparts, has no contraindications to the appointment. The only exception is individual intolerance to the active or auxiliary components of the drug.

During clinical trials and open sales, no serious side effects have been identified. But in people with protein intolerance, the Kipferon candle can cause allergies in the form of a small rash on the skin, redness or itching.

The following negative reactions can also be observed:

• a symptomatic picture that resembles a flu infection - muscle pain, migraine, aching bones, fever;
• Exacerbation of chronic viruses;
• Feeling of a foreign object in the rectum;
• Burning and itching in the vagina.

The instruction states that these phenomena are not dangerous and do not require cancellation or replacement with a more expensive or cheaper analogue.

The use of Kipferon helps to get rid of a large number of serious diseases. If there are negative reactions to the drug or its price seems too high, the doctor will select a substitute with a similar effect and composition. But when buying an analogue, it is worth remembering that the Kipferon candle has a more powerful effect than another drug. It is worth considering the decision well, perhaps by saving a ruble on the original medication, you will lose more due to long-term treatment.